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Bacteria as living factories for the production of powerful antibiotics

[12-07-2018]

By definition, antibiotics kill bacteria. Nevertheless, TU Delft researchers have succeeded in engineering bacteria to produce promising amounts of a simple carbapenem antibiotic. Carbapenem antibiotics are effective against many bacteria and are usually only used when other antibiotics fail. They are currently only produced synthetically – an expensive process that also leads to chemical waste. This research suggests that by using bacteria as ‘living factories’, carbapenems might also be produced biologically. read more