PROGRAM

Casimir course - Theoretical Biophysics

Date:

Time:

3:45 - 5:30 PM

Location:

Leiden, Huygens building (Niels Bohrweg 2), room HL 204

 

Course content
This course provides a theorist's perspective on biophysics. There is an explosion of data from extremely sophisticated experiments (e.g. single molecules experiments) that, in order to be interpreted, require a theoretical understanding on the basis of statistical mechanics.

Instead of trying to provide a broad overview over the molecular biology of the whole cell, I shall focus on the molecules that are involved in the so-called central dogma: information flows from DNA via RNA to proteins. The common structure of these molecules is that they are polymers.

More specifically I discuss: polymer physics, DNA melting, DNA-protein complexes (especially nucleosomes and protein-target search), kinetic proofreading for transcription.


Audience
The course is intended for the PhD students and postdocs associated to the Casimir Research School but is also appropriate for Masters students. Both, more theoretically and more experimentally oriented student should profit from this course.


Organization
There will be reading assignments and homework.


Teachers
Prof. dr. Helmut Schiessel


Literature
H. Schiessel (2014): Biophysics for Beginners: a Journey through the Cell Nucleus, Pan Stanford Publishing (ISBN-13: 978-9814241656) is recommended but not mandatory.


Credits: 5 GSC.


Schedule
The course starts on January 31st and will take place (nearly) every Tuesday afternoon (3:45-5:30 PM) up until May 2nd. The course will be given in Leiden, Huygens building (Niels Bohrweg 2), room HL 204.

 

Register here

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Events

26 - 30 June 2017

BioBusiness Summer Schoollink

20 July 2017

Casimir Cafélink

21 - 25 August 2017

Topological Matter School 2017link

Workshops

29 March 2011 - 1 January 2018

Casimir Course: Hot Topicslink