Settling a controversy surrounding termination of DNA replication (article in Nature Chemical Biology by Delft/BN Nynke Dekker lab)


Researchers from the Nynke Dekker lab at BN, together with three researchers from the University of Wollongong in Australia, have shed light on the manner in which the process of DNA replication is stopped in E.coli. Key player in this process is the Tus–Ter system, a protein–DNA complex that forms a molecular roadblock that can withstand a collision with the fast-moving replication machinery.

The researchers solved an existing controversy that surrounded the mechanism of roadblock formation. An article on this research appeared this week in Nature Chemical Biology

Read the article here.